The 49ers will likely do the smart thing tomorrow and run the ball a lot trying to keep the ball away from the Cardinals.  Frank Gore will likely be very tired Sunday Night but the Cardinals better also bruise him up some if they want to win this game.  Shaun Hill is a good play action passer so look for Isaac Bruce, Josh Morgan and Arnaz Battle to possibly get deep if the Niners establish the running game early.  Maybe this will be the game that Vernon Davis breaks out as the Cards’ OLBs are a little long in tooth (Clark Haggans and Chike Okeafor).

The Cardinals would like to run the ball a little more this season with Tim Hightower and Beanie Wells.  They might not have much luck against Patrick Willis though as he’s a tackling machine.   With that in mind the Cards might just attack the Niners D with Larry Fitzgerald, Anquan Boldin and Steve Breaston.  Kurt Warner should pile up some huge stats in this game.

PREDICITION:  ARIZONA CARDINALS 34, SAN FRANCISCO 49ERS 30